What Is Transdermal?
Transdermal refers to delivery of a substance through the skin into the bloodstream, bypassing the digestive system. It is used for medications, supplements, and cosmetic applications.
Classification: Other › Transdermal
Key Takeaway
Transdermal delivery has real pharmacology behind it. Not all substances penetrate skin equally, and claims need to be weighed against actual skin penetration data.
Why This Matters
Transdermal drug delivery is well established for medications like nicotine patches, hormone patches, and some pain medications. Effectiveness depends on molecular size, fat solubility, and formulation. In natural health, transdermal magnesium oils, essential oils, and herbal salves are popular, though absorption rates vary by compound. Some claims of high transdermal absorption for nutrients are more marketing than science. As a practical matter, the skin is an effective barrier against most large, water-soluble molecules.
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Frequently Asked Questions
What does transdermal mean?
Delivery of a substance through the skin into the bloodstream, bypassing the digestive system.
What medications are transdermal?
Nicotine patches, hormone patches, some pain medications like fentanyl, motion sickness patches, and others.
Do transdermal supplements work?
It depends on the substance. Some small, fat-soluble molecules can cross skin effectively. Many marketed “transdermal” supplements have limited real absorption.
