Albumin

What Is Albumin?

Albumin is the most abundant protein in blood plasma. It maintains fluid balance, transports hormones and drugs, and is used clinically as a replacement fluid in some conditions.

Classification: Other › Albumin

Key Takeaway

Albumin plays many roles in circulation. Low serum albumin often signals malnutrition, liver disease, or chronic inflammation.

Why This Matters

Albumin is made by the liver and makes up about half of the protein content in plasma. It holds water in the bloodstream through colloid osmotic pressure, transports hormones, fatty acids, bilirubin, and many medications, and acts as a buffer. Low serum albumin can indicate liver disease, kidney protein loss, malnutrition, or chronic inflammation. Intravenous albumin is used clinically in certain fluid-shift conditions and in therapeutic plasma exchange.

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Frequently Asked Questions

What is albumin?

The most abundant blood plasma protein, made by the liver. It maintains fluid balance, transports many substances, and acts as a buffer.

Why would my albumin be low?

Low serum albumin can reflect liver disease, kidney protein loss, malnutrition, or chronic inflammation.

What is albumin used for medically?

Intravenous albumin is used in certain fluid-balance conditions and as a replacement fluid during therapeutic plasma exchange.